Education
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2023-Present MSSabanci University
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2023 BS Yıldız Technical University
Research Experience
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2023 - Present Graduate Researcher | Computational Biology Laboratory, Sabancı University
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Working on the evolution of DNA repair proteins by using computational methods and trying to derive meaningful information by reinterpreting protein data and revealing the effects of protein evolution on functional properties.
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Performed an exhaustive phylogenetic analysis to infer the evolutionary history of XPA protein across all eukaryotic species with sequenced genomes.
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2021-2022 Undergraduate Researcher | Bioinformatics Laboratory, Yıldız Technical University
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Did an exhaustive computational analysis about ANGPTL4 protein which plays role in lipid metabolism via gut microbiome.
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Utilized various in silico tools to analyze potential mutations of protein.
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Work Experience
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2023 - Present Graduate Teaching Assistant | Sabancı University
- Taught classes: Introduction to Bioinformatics, Computational Approaches to Problem Solving
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2022 Research Intern | Bioinformatics Laboratory, Yıldız Technical University
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Retrieved protein data from NCBI Virus database and learned how to analyze it.
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Utilized Python to analyze mutations in the spike protein of SARS-CoV-2.
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Identified single-point mutations and calculated mutation percentages across globe.
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Employed various in silico tools to analyze potential mutations at common points across all continents.
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Publications
- Kose, C., Cao, X., Dewey, E. B., Malkoç, M., Adebali, O., Sekelsky, J., Lindsey-Boltz, L. A., & Sancar, A. (2024). Cross-species investigation into the requirement of XPA for nucleotide excision repair. Nucleic acids research, 52(2), 677–689. https://doi.org/10.1093/nar/gkad1104